Differential expression of interleukin‐2 receptors (α and β chain) in mature lymphoid neoplasms

doi:10.1002/ajh.2830460304

Article

Differential expression of interleukin‐2 receptors (α and β chain) in mature lymphoid neoplasms

1 Jul 1994

Abstract excerpt

We investigated the expression of interleukin-2 receptors (IL-2R) in 60 adult patients with mature lymphoid neoplasms by flow cytometric analysis, using two monoclonal antibodies, anti-Tac for IL-2R alpha-chain (IL-2R alpha) and Mik-beta 1 for IL-2R beta-chain (IL-2R beta). Among B-cell malignancies, IL-2R alpha was found in 13/25 (52%) cases of chronic lymphocytic leukemia (CLL) and its variants, 3/14 (21%) of a...

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