Article
Association of human platelet alloantigen 1 through 5 polymorphisms with ischemic stroke.
Cerebrovascular diseases (Basel, Switzerland) - 1 Jan 2008
Saidi Sarra, Mahjoub Touhami, Slamia Lamia B, Ammou Sofyan B, Al-Subaie Abeer M, Almawi Wassim Y
Abstract excerpt
Polymorphisms in human platelet alloantigen (HPA)-1 and HPA-3 (GPIIb/IIIa), HPA-2 (GPIb/IX), HPA-4 (GPIIIa) and HPA-5 (GPIa/IIa) were investigated in 216 stroke patients and 318 matched control subjects. HPA genotyping was done by the polymerase chain reaction method using sequence-specific primers. Higher frequencies of the HPA-1 a/b (p < 0.001) and HPA-5 a/b (p < 0.001) allele, together with HPA-1 b/b, HPA-5...
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