Association of scleroderma with a T cell antigen receptor gamma gene restriction fragment length polymorphism.

doi:10.1002/art.1780330415

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Article

Association of scleroderma with a T cell antigen receptor gamma gene restriction fragment length polymorphism.

Arthritis and rheumatism - 1 Apr 1990

Kratz L E, Boughman J A, Pincus T, Cohen D I, Needleman B W

Abstract excerpt

Restriction fragment length polymorphisms (RFLPs) in the T cell receptor (TCR) alpha, beta, and gamma genes were analyzed in 61 scleroderma patients and 150 controls. An association was found between scleroderma and an 11.3-kb Pvu II fragment in the TCR gamma gene; this gene was found in 41.0% of...

Topics

Alleles
Black People
Gene Frequency
Genotype
Humans
Polymorphism, Restriction Fragment Length
Receptors, Antigen, T-Cell
Scleroderma, Systemic

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