Article
Peripheral Thy1+ lymphocytes rearranging TCR-gammadelta genes in LAT-deficient mice.
European journal of immunology - 1 Sept 2009
Miazek Arkadiusz, Macha Kornelia, Łaszkiewicz Agnieszka, Kissenpfennig Adrien, Malissen Bernard, Kisielow Pawel
Abstract excerpt
Linker for activation of T cells (LAT) is an adaptor molecule indispensable for development of alphabeta and gammadelta T lymphocytes. Surprisingly, using a new model of LAT-deficient mice we found that despite arrested thymic development, a discrete population of cells with active Lat promoter,...
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