Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Acetylation Level of Histone H3 in Early Embryonic Stages Affects Subsequent Development of Miniature Pig Somatic Cell Nuclear Transfer Embryos

1 Jan 2009

Abstract excerpt

Successful cloning by somatic cell nuclear transfer (SCNT) requires a reprogramming process in which the epigenetic state of a differentiated donor nucleus must be converted into an embryonic totipotent state. However, this epigenetic reprogramming is incomplete in SCNT embryos, causing low production efficiency. Recently, it has been reported that trichostatin A (TSA), an inhibitor of histone deacetylase,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CRISPR and Genetic Engineering
Share to Pluripotent Stem Cells Research
Share to Reproductive Biology and Fertility

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19700928
DOI: 10.1262/jrd.20245

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Acetylation Level of Histone H3 in Early Embryonic Stages Affects Subsequent Development of Miniature Pig Somatic Cell Nuclear Transfer EmbryosPMID 19700928Read ↗

Trichostatin A Promotes the Development of Bovine Somatic Cell Nuclear Transfer EmbryosSemantic proximity Read ↗

Trichostatin A Improves Histone Acetylation in Bovine Somatic Cell Nuclear Transfer Early EmbryosSemantic proximity Read ↗

Simultaneous Inhibition of Histone Deacetylases and RNA Synthesis Enables Totipotency Reprogramming in Pig SCNT EmbryosSemantic proximity Read ↗

Histone Deacetylase Inhibitors Improve <i>In Vitro</i> and <i>In Vivo</i> Developmental Competence of Somatic Cell Nuclear Transfer Porcine EmbryosSemantic proximity Read ↗

An Epigenetic Modifier Results in Improved <i>In Vitro</i> Blastocyst Production after Somatic Cell Nuclear TransferSemantic proximity Read ↗

Trichostatin A and nuclear reprogramming of cloned rabbit embryos1Semantic proximity Read ↗

Trichostatin A Improved Epigenetic Modifications of Transfected Cells but did not Improve Subsequent Cloned Embryo DevelopmentSemantic proximity Read ↗

BIX-01294 increases pig cloning efficiency by improving epigenetic reprogramming of somatic cell nucleiSemantic proximity Read ↗

Trichostatin A affects histone acetylation and gene expression in porcine somatic cell nucleus transfer embryosSemantic proximity Read ↗

MC1568 Enhances Histone Acetylation During Oocyte Meiosis and Improves Development of Somatic Cell Nuclear Transfer Embryos in PigSemantic proximity Read ↗

Quisinostat treatment improves histone acetylation and developmental competence of porcine somatic cell nuclear transfer embryosSemantic proximity Read ↗

Oxamflatin Improves Developmental Competence of Porcine Somatic Cell Nuclear Transfer EmbryosSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.