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Trichostatin A and nuclear reprogramming of cloned rabbit embryos1

2 Feb 2008

Abstract excerpt

To investigate the influence of histone deacetylases on nuclear reprogramming after nuclear transfer, we treated the cloned embryos with a histone deacetylase inhibitor, Trichostatin A (TSA). In the present study, global changes in acetylation of histone H3-lysine 14, histone H4-lysine 12, and histone H4-lysine 5 were studied in rabbit in vivo fertilized embryos, somatic cell nuclear transfer (SCNT) embryos, and...

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Identifiers

PMID: 18245503
DOI: 10.2527/jas.2007-0718

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Trichostatin A and nuclear reprogramming of cloned rabbit embryos1PMID 18245503Read ↗

Trichostatin A (TSA) improves the development of rabbit‐rabbit intraspecies cloned embryos, but not rabbit‐human interspecies cloned embryosSemantic proximity Read ↗

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The Effects of Trichostatin A on mRNA Expression of Chromatin Structure-, DNA Methylation-, and Development-Related Genes in Cloned Mouse BlastocystsSemantic proximity Read ↗

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Effect of Trichostatin A on Chromatin Remodeling, Histone Modifications, DNA Replication, and Transcriptional Activity in Cloned Mouse Embryos1Semantic proximity Read ↗

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