Article
Single institute study of FLT3 mutation in acute myeloid leukemia with near tetraploidy in Serbia.
Journal of genetics - 1 Aug 2009
Jurisić Vladimir, Pavlović Sonja, Colović Natasa, Djordjevic Vesna, Bunjevacki Vera, Janković Gradimir, Colović Milica
Abstract excerpt
Patients with de novo acute myeloid leukemia (AML) and near-tetraploid or completely tetraploid karyotype at presentation are rare. We present four patients with near-tetraploidy/tetraploidy in a cohort of 426 consecutive AML patients (0.98%) in respect to their cytogenetic findings, immunophenotype pattern, response to chemotherapy, course of disease and molecular analyses including tyrosine kinase receptor FLT3...
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