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Article

Near-triploid and near-tetraploid acute lymphoblastic leukemia of childhood.

Blood - 1 Aug 1990

Pui C H, Carroll A J, Head D, Raimondi S C, Shuster J J, Crist W M, Link M P, Borowitz M J, Behm F G, Land V J

Abstract excerpt

Cytogenetic and DNA flow cytometric analyses of leukemic cells from 1,971 children with newly diagnosed acute lymphoblastic leukemia (ALL) identified stem lines with modal chromosome numbers greater than 65 in 26 patients (1.3%). Near-triploidy (66 to 73 chromosomes) was found in six cases and near-tetraploidy (82 to 94 chromosomes) in 20. A striking morphologic finding was the presence of clumped chromatin with...

Topics

Adolescent
Child
Child, Preschool
DNA
Female
Flow Cytometry
Humans
Karyotyping
Male
Phenotype
Ploidies
Precursor Cell Lymphoblastic Leukemia-Lymphoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Prognosis

T-Lymphocytes

Source

Identifiers

PMID: 2378987

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2378987-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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