Clinicopathological analysis of near-tetraploidy/tetraploidy acute myeloid leukaemia.

doi:10.1136/jclinpath-2014-202697

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Article

Clinicopathological analysis of near-tetraploidy/tetraploidy acute myeloid leukaemia.

Journal of clinical pathology - 1 Mar 2015

Pang Changlee S, Pettenati Mark J, Pardee Timothy S

Abstract excerpt

AIMS: Near-tetraploidy/tetraploidy (NT/T) is a rare cytogenetic alteration in acute myeloid leukaemia (AML). NT/T-AML is categorised as complex cytogenetics and therefore, presumed to have an unfavourable prognosis. Our aim is to further characterise the clinical, morphological, cytogenetic and prognostic features of NT/T-AML. METHODS: We searched our cytogenetic laboratory database from 1991 to 2012 to reveal 13...

Topics

Adult
Aged
Cytogenetics
Databases, Factual
Female
Genetic Predisposition to Disease
Humans
Karyotype
Leukemia, Myeloid, Acute
Male
Middle Aged
Phenotype
Remission Induction
Risk Factors
Tetraploidy
Time Factors
Treatment Outcome

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Identifiers

PMID: 25563333
DOI: 10.1136/jclinpath-2014-202697
PMCID: PMC4886850

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