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Article

APOBEC3B deletion and risk of HIV-1 acquisition.

The Journal of infectious diseases - 1 Oct 2009

An Ping, Johnson Randall, Phair John, Kirk Gregory D, Yu Xiao-Fang, Donfield Sharyne, Buchbinder Susan, Goedert James J, Winkler Cheryl A

Abstract excerpt

The human APOBEC3 family of cytidine deaminases provides intrinsic immunity to retroviral infection. A naturally occurring 29.5-kb deletion removes the entire APOBEC3B gene. We examined the impact of the APOBEC3B gene deletion in >4000 individuals from 5 human immunodeficiency virus type 1 (HIV-1) natural history cohorts. The hemizygous genotype had no effect on either acquisition of HIV-1 infection or...

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Source

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Identifiers

PMID: 19698078
DOI: 10.1086/605644
PMCID: PMC3690486

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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