Article
Support of association between BRD1 and both schizophrenia and bipolar affective disorder.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Mar 2010
Nyegaard Mette, Severinsen Jacob E, Als Thomas D, Hedemand Anne, Straarup Steen, Nordentoft Merete, McQuillin Andrew, Bass Nicholas, Lawrence Jacob, Thirumalai Srinivasa, Pereira Ana C P, Kandaswamy Radhika, Lydall Gregory J, Sklar Pamela, Scolnick Edward, Purcell Shaun, Curtis David, Gurling Hugh M D, Mortensen Preben B, Mors Ole, Børglum Anders D
Abstract excerpt
A recent study published by our group implicated the bromodomain containing protein 1 (BRD1) gene located at chromosome 22q13.33 with schizophrenia (SZ) and bipolar affective disorder (BPD) susceptibility and provided evidence suggesting a possible role for BRD1 in neurodevelopment. The present study reports an association analysis of BRD1 and the neighboring gene ZBED4 using a Caucasian case-control sample from...
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