Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inherited quantitative DNA variation in the LPA ("apolipoprotein (a)") gene.

Clinical genetics - 1 Feb 1990

Kondo I, Berg K

Abstract excerpt

The Lp(a) antigen resides in a polypeptide chain that is attached to apolipoprotein B (apoB) by a disulfide bridge. Recently, cDNA for this polypeptide chain (frequently referred to as the Lp(a) polypeptide chain, Lp(a) apolipoprotein or apolipoprotein (a] was cloned and extensive homology to plasminogen was uncovered. This homology creates significant difficulties in studying DNA variation in the gene (the LPA...

Topics

Adult
Child
Chromosome Mapping
DNA
DNA Probes
Female
Genetic Variation
Humans
Lipoprotein(a)
Lipoproteins
Male
Peptide Fragments
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Restriction Fragment Length

Twins, Monozygotic

Source

Identifiers

PMID: 1968792
DOI: 10.1111/j.1399-0004.1990.tb03490.x

Genes

LPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1968792-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inherited quantitative DNA variation in the LPA ("apolipoprotein (a)") gene.PMID 1968792Read ↗

The apolipoprotein (a) gene: a transcribed hypervariable locus controlling plasma lipoprotein (a) concentration.Semantic proximity Read ↗

Restriction site polymorphism at the LPA (Lp(a) apolipoprotein; apolipoprotein (a)) locus.Semantic proximity Read ↗

LPA and PLG sequence variation and kringle IV-2 copy number in two populations.Semantic proximity Read ↗

Genetic basis and pathophysiological implications of high plasma Lp(a) levels.Semantic proximity Read ↗

Apolipoprotein(a) gene accounts for greater than 90% of the variation in plasma lipoprotein(a) concentrations.Semantic proximity Read ↗

[Molecular patho-biochemistry and genetic diagnosis for plasminogen-apolipoprotein (a) gene family related to atherosclerosis and thrombosis].Semantic proximity Read ↗

[Apolipoprotein (a)].Semantic proximity Read ↗

Lipoprotein (a): impact by ethnicity and environmental and medical conditions.Semantic proximity Read ↗

Lp(a) concentrations are related to plasma lipid concentrations.Semantic proximity Read ↗

Assessment of Apolipoprotein(a) Isoform Size Using Phenotypic and Genotypic Methods.Semantic proximity Read ↗

Molecular definition of the extreme size polymorphism in apolipoprotein(a).Semantic proximity Read ↗

Structural and functional polymorphism of lipoprotein(a): biological and clinical implications.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.