Article
Restriction site polymorphism at the LPA (Lp(a) apolipoprotein; apolipoprotein (a)) locus.
Clinical genetics - 1 Jun 1990
Berg K, Kondo I, Drayna D, Lawn R
Abstract excerpt
A restriction site polymorphism in the Lp(a) apolipoprotein gene (the LPA gene) is reported. The basis for the polymorphism is presence or absence of an MspI restriction site that appears to be 3' to the last kringle IV structure of the gene. The "1" gene (presence of the restriction site) has a frequency of 0.316 and the "2" gene (absence of the restriction site) has a frequency of 0.684. Both members of each of...
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