Article
The immunopathogenesis of Crohn's disease: a three-stage model.
Current opinion in immunology - 1 Oct 2009
Sewell Gavin W, Marks Daniel Jb, Segal Anthony W
Abstract excerpt
The pathogenesis of Crohn's disease (CD) has remained an enigma for at least a century. There was considerable optimism that genetic linkage and genome-wide association (GWA) studies had identified genes causally responsible. However, the realisation that these genes make a relatively minor contr...
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