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Article

[TDP-43 proteinopathies, toward understanding of the molecular pathogenesis].

Rinsho shinkeigaku = Clinical neurology - 1 Nov 2009

Hasegawa Masato, Nonaka Takashi, Yamashita Makiko, Kametani Fuyuki, Arai Tetsuaki, Yoshida Mari, Hashizume Yoshio, Tsuchiya Kuniaki, Akiyama Haruhiko

Abstract excerpt

The TDP-43 proteinopathies: Toward understanding of the molecular pathogenesis. TAR DNA binding protein of 43 kDa (TDP-43), a heterogeneous nuclear ribonucleoprotein was identified as a major component of ubiquitin-positive inclusions in FTLD and ALS, and the concept of TDP-43 proteinopathies was proposed. Immunoblot and immunohistochemical analyses using multiple anti-phosphorylated TDP-43 antibodies revealed...

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Identifiers

PMID: 20030209
DOI: 10.5692/clinicalneurol.49.783

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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