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Article

Genetic variations of PIP4K2A confer vulnerability to poor antipsychotic response in severely ill schizophrenia patients.

PloS one - 1 Jan 2014

Kaur Harpreet, Jajodia Ajay, Grover Sandeep, Baghel Ruchi, Gupta Meenal, Jain Sanjeev, Kukreti Ritushree

Abstract excerpt

Literature suggests that disease severity and neurotransmitter signaling pathway genes can accurately identify antipsychotic response in schizophrenia patients. However, putative role of signaling molecules has not been tested in schizophrenia patients based on severity of illness, despite its biological plausibility. In the present study we investigated the possible association of polymorphisms from five...

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Source

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Identifiers

PMID: 25025909
DOI: 10.1371/journal.pone.0102556
PMCID: PMC4099378

Genes

BDNF
RGS4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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