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Article

Processing and presentation of variant surface glycoprotein molecules to T cells in African trypanosomiasis.

Journal of immunology (Baltimore, Md. : 1950) - 1 Sept 2009

Dagenais Taylor R, Freeman Bailey E, Demick Karen P, Paulnock Donna M, Mansfield John M

Abstract excerpt

Th1 cell responses to the variant surface glycoprotein (VSG) of African trypanosomes play a critical role in controlling infection through the production of IFN-gamma, but the role of APCs in the induction and regulation of T cell-mediated protection is poorly understood. In this study, we have investigated the Ag presentation capabilities of dendritic cells (DCs) and macrophages during early trypanosome...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Histocompatibility Antigens Class II

Share to Macrophages, Peritoneal

Share to Mice, Inbred C3H

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Share to Trypanosomiasis, African

Source

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Identifiers

PMID: 19675169
DOI: 10.4049/jimmunol.0802005
PMCID: PMC2730433

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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