Article
Alternative versus classical macrophage activation during experimental African trypanosomosis.
Journal of leukocyte biology - 1 Mar 2001
Namangala B, De Baetselier P, Noël W, Brys L, Beschin A
Abstract excerpt
The type I/type II cytokine balance may influence the development of different subsets of suppressive macrophages, i.e., classically activated macrophages (caMphi, type I) versus alternatively activated macrophages (aaMphi, type II). Recently, we showed that although mice infected with phospholipase C-deficient (PLC-/-) Trypanosoma brucei brucei exhibit a clear shift from type I to the type II cytokine...
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