Kinetic analysis of antigen-specific immune responses in resistant and susceptible mice during infection with Trypanosoma cruzi.

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Article

Kinetic analysis of antigen-specific immune responses in resistant and susceptible mice during infection with Trypanosoma cruzi.

Journal of immunology (Baltimore, Md. : 1950) - 15 Dec 1993

Hoft D F, Lynch R G, Kirchhoff L V

Abstract excerpt

The Tulahuén strain of Trypanosoma cruzi has been shown previously to cause higher parasitemias and greater mortality in BALB/c mice compared with C57BL6/J mice. The goal of our study was to determine whether different cytokine responses to parasite Ag during T. cruzi infection correlate with the susceptible and resistant phenotypes identified in these mice. At several time points after initial infection with...

Topics

Animals
Antigens, Protozoan
Chagas Disease
Cytokines
Female
Interferon-gamma
Interleukin-2
Interleukin-4
Interleukin-5
Kinetics
Lymphocyte Activation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lymphocytes

Mice

Mice, Inbred BALB C

Mice, Inbred C57BL

Phenotype

Species Specificity

Trypanosoma cruzi

Source

Open in PubMed

Identifiers

PMID: 8258708

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8258708-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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