Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Altered CD4+ T cell phenotype and function determine the susceptibility to mucosal candidiasis in transgenic mice expressing HIV-1.

Journal of immunology (Baltimore, Md. : 1950) - 1 Jul 2006

Lewandowski Daniel, Marquis Miriam, Aumont Francine, Lussier-Morin Annie-Claude, Raymond Marianne, Sénéchal Serge, Hanna Zaher, Jolicoeur Paul, de Repentigny Louis

Abstract excerpt

The impairments of protective mucosal immunity which cause susceptibility to oropharyngeal candidiasis (OPC) in HIV infection remain undefined. This study used a model of OPC in CD4C/HIV MutA transgenic (Tg) mice expressing Rev, Env, and Nef of HIV-1 to investigate the role of transgene expressing dendritic cells (DCs) and CD4+ T cells in maintenance of chronic oral carriage of Candida albicans. DCs were depleted...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adoptive Transfer
Share to Candidiasis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Immunity, Mucosal

Share to Immunologic Memory

Share to Lymph Nodes

Share to Mouth Mucosa

Share to Phagocytosis

Source

Identifiers

PMID: 16785545
DOI: 10.4049/jimmunol.177.1.479

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Altered CD4+ T cell phenotype and function determine the susceptibility to mucosal candidiasis in transgenic mice expressing HIV-1.PMID 16785545Read ↗

Selective Expression of Human Immunodeficiency Virus Nef in Specific Immune Cell Populations of Transgenic Mice Is Associated with Distinct AIDS-Like PhenotypesSemantic proximity Read ↗

Evidence for Differential Expression ofCandida albicansVirulence Genes during Oral Infection in Intact and Human Immunodeficiency Virus Type 1–Transgenic MiceSemantic proximity Read ↗

Dectin-1 isoforms contribute to distinct Th1/Th17 cell activation in mucosal candidiasis.Semantic proximity Read ↗

Insights into the Role of Innate Immunity in Cervicovaginal Papillomavirus Infection from Studies Using Gene-Deficient MiceSemantic proximity Read ↗

Biphasic Regulation of Epithelial Antimicrobial Peptides during <em>Candida albicans</em> Vaginal Infection: Distinct Contributions of NLRP3/IL-1β and IL-17RA Pathways to β-Defensin-1 and -3 ExpressionSemantic proximity Read ↗

Estradiol impairs the Th17 immune response against Candida albicansSemantic proximity Read ↗

Resistance of T-Cell Receptor δ-Chain-Deficient Mice to ExperimentalCandidaalbicansVaginitisSemantic proximity Read ↗

Candidiasis in interferon-gamma knockout (IFN-gamma-/-) mice.Semantic proximity Read ↗

Susceptibility of Immature and Mature Langerhans Cell-Type Dendritic Cells to Infection and Immunomodulation by Human CytomegalovirusSemantic proximity Read ↗

Mouse papillomavirus infection persists in mucosal tissues of an immunocompetent mouse strain and progresses to cancerSemantic proximity Read ↗

Cannabidiol prevents mucosal HIV-1 transmission by targeting Langerhans cells, dendritic cells, macrophages and T-cellsSemantic proximity Read ↗

Oral mucosal Langerhans' cells as target, effector and vector in HIV infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.