Article
Caveolin-1 and altered neuregulin signaling contribute to the pathophysiological progression of diabetic peripheral neuropathy.
Diabetes - 1 Nov 2009
McGuire James F, Rouen Shefali, Siegfreid Eric, Wright Douglas E, Dobrowsky Rick T
Abstract excerpt
OBJECTIVE: Evaluate if Erb B2 activation and the loss of caveolin-1 (Cav1) contribute to the pathophysiological progression of diabetic peripheral neuropathy (DPN). RESEARCH DESIGN AND METHODS: Cav1 knockout and wild-type C57BL/6 mice were rendered diabetic with streptozotocin, and changes in mot...
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