Article
Phenotypic changes in diabetic neuropathy induced by a high-fat diet in diabetic C57BL/6 mice.
Experimental diabetes research - 1 Jan 2011
Guilford B L, Ryals J M, Wright D E
Abstract excerpt
Emerging evidence suggests that dyslipidemia is an independent risk factor for diabetic neuropathy (DN) (reviewed by Vincent et al. 2009). To experimentally determine how dyslipidemia alters DN, we quantified neuropathic symptoms in diabetic mice fed a high-fat diet. Streptozotocin-induced diabetic C57BL/6 mice fed a high-fat diet developed dyslipidemia and a painful neuropathy (mechanical allodynia) instead of...
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