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Article

Abi plays an opposing role to Abl in Drosophila axonogenesis and synaptogenesis.

Development (Cambridge, England) - 1 Sept 2009

Lin Tzu-Yang, Huang Chiu-Hui, Kao Hsiu-Hua, Liou Gan-Guang, Yeh Shih-Rung, Cheng Chih-Ming, Chen Mei-Hsin, Pan Rong-Long, Juang Jyh-Lyh

Abstract excerpt

Abl tyrosine kinase (Abl) regulates axon guidance by modulating actin dynamics. Abelson interacting protein (Abi), originally identified as a kinase substrate of Abl, also plays a key role in actin dynamics, yet its role with respect to Abl in the developing nervous system remains unclear. Here we show that mutations in abi disrupt axonal patterning in the developing Drosophila central nervous system (CNS)....

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PMID: 19675132
DOI: 10.1242/dev.033324

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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