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Article

Separate respiratory phenotypes in methyl-CpG-binding protein 2 (Mecp2) deficient mice.

Pediatric research - 1 Apr 2006

Bissonnette John M, Knopp Sharon J

Abstract excerpt

Rett syndrome (RTT) is a neurodevelopmental disorder caused by mutations in the X-linked gene methyl-CpG-binding protein 2 (MECP2) that encodes a DNA binding protein involved in gene silencing. Selective deletion of Mecp2 in post-mitotic neurons in mice results in a Rett-like phenotype characterized by disturbances in motor activity and body weight, suggesting that these symptoms are exclusively caused by...

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Source

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Identifiers

PMID: 16549521
DOI: 10.1203/01.pdr.0000203157.31924.4a
PMCID: PMC1473964

Genes

MECP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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