Article

Defining dysfunction due to loss of MECP2 in Rett Patient Brain

2021-08-24

Abstract excerpt

Rett Syndrome is characterized by a postnatal loss of neurophysiological function and regression of childhood development. Because the syndrome is X-linked and males with MECP2 mutations generally do not survive birth, the study of this syndrome has been complicated by the fact that in female brain, a portion of neurons express wild type MECP2, and another portion express a non-functional allele of MECP2. Therefor...

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Literature Corpus work: c5b3ba03-877a-5388-9c5d-af0b309b4a14
DOI: 10.1101/2021.08.24.457297

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