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Article

NF-kappaB activation, dependent on acetylation/deacetylation, contributes to HIF-1 activity and migration of bone metastatic breast carcinoma cells.

Molecular cancer research : MCR - 1 Aug 2009

Bendinelli Paola, Matteucci Emanuela, Maroni Paola, Desiderio Maria Alfonsina

Abstract excerpt

Here, we show that NF-kappaB-HIF-1 interaction contributed to breast cancer metastatic capacity by means of an incomplete epithelial/mesenchymal transition and influencing migration, as shown in 1833 (human) and 4T1 (mouse) metastatic cells after different stimuli. The 1833 and the transforming g...

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Share to Acetylation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hypoxia-Inducible Factor 1

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Share to NF-KappaB Inhibitor alpha

Share to Proto-Oncogene Proteins c-jun

Share to Proto-Oncogene Proteins pp60(c-src)

Source

Identifiers

PMID: 19671685
DOI: 10.1158/1541-7786.MCR-08-0548

Genes

HDAC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19671685-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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