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Breast Cancer–Amplified Sequence 3, a Target of Metastasis-Associated Protein 1, Contributes to Tamoxifen Resistance in Premenopausal Patients with Breast Cancer

19 Jun 2006

Abstract excerpt

Lysine acetylation occurs in many protein targets, including core histones, transcription factors, and other proteins. Metastasis-associated protein 1 (MTA1) is implicated in the progression and metastasis of various epithelial tumors. Because MTA1 functions as a transcriptional coregulator, much of its role in cancer promoting processes are likely to involve its ability to regulate the transcription of...

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Share to Epigenetics and DNA Methylation
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PMID: 16855396
DOI: 10.4161/cc.5.13.2924

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