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Article

NF-kappaB Is Involved in the Regulation of EMT Genes in Breast Cancer Cells

20 Jan 2017

Abstract excerpt

The metastatic process in breast cancer is related to the expression of the epithelial-to-mesenchymal transition transcription factors (EMT-TFs) SNAIL, SLUG, SIP1 and TWIST1. EMT-TFs and nuclear factor-κB (NF-κB) activation have been associated with aggressiveness and metastatic potential in carcinomas. Here, we sought to examine the role of NF-κB in the aggressive properties and regulation of EMT-TFs in human...

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PMID: 28107418
DOI: 10.1371/journal.pone.0169622

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