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Article

Two‐stage genome‐wide association study of chronic rhinosinusitis and disease subphenotypes highlights mucosal immunity contributing to risk

3 Jan 2021

Abstract excerpt

Chronic rhinosinusitis (CRS) is a prevalent inflammatory disease that results in over $10 billion in health-care costs annually in the United States. CRS (and its most severe form, nasal polyposis [NP]) overlaps clinically with asthma and aspirin-exacerbated respiratory disease (AERD). Despite having an enormous public health impact, the underlying molecular mechanisms of CRS remain unknown. That CRS has a...

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PMID: 33393196
DOI: 10.1002/alr.22731

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