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Article

Significance of EGFR signaling pathway genetic alterations in radically resected non-small cell lung cancers from a Polish cohort. One institutional study.

Advances in medical sciences - 1 Sept 2015

Kowalczuk Oksana, Kozlowski Miroslaw, Milewski Robert, Minarowski Lukasz, Reszec Joanna

Abstract excerpt

PURPOSE: We evaluated the distribution and clinical impact of EGFR, KRAS and HER2 copy number gains and EGFR, KRAS and BRAF activating mutations in resected non-small cell lung cancers (NSCLCs) from 151 Polish patients. MATERIALS AND METHODS: Quantitative PCR and DNA sequencing were used for copy number evaluation and mutational analysis, respectively. RESULTS: An increased EGFR CN was found in 21.2% of the...

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Identifiers

PMID: 26118982
DOI: 10.1016/j.advms.2015.05.004

Genes

EGFR
KRAS
BRAF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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