Article
Understanding inflammatory bowel disease via immunogenetics.
Journal of autoimmunity - 1 Nov 2015
de Lange Katrina M, Barrett Jeffrey C
Abstract excerpt
The major inflammatory bowel diseases, Crohn's disease and ulcerative colitis, are both debilitating disorders of the gastrointestinal tract, characterized by a dysregulated immune response to unknown environmental triggers. Both disorders have an important and overlapping genetic component, and much progress has been made in the last 20 years at elucidating some of the specific factors contributing to disease...
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