Article
A-form DNA structure is a determinant of transcript levels from the Xenopus gata2 promoter in embryos.
Biochimica et biophysica acta - 1 Jan 2000
Llewellyn Katrina J, Cary Peter D, McClellan James A, Guille Matthew J, Scarlett Garry P
Abstract excerpt
We have previously shown that a critical region of the gata2 promoter contains an inverted CCAAT box and adopts a partial A-form DNA structure in vitro. At gastrula stages of development transcription requires binding of CBTF (CCAAT box transcription factor), a multi-subunit transcription factor, to this region. Xilf3 is one component of CBTF and the double stranded RNA binding domains (dsRBDs) of Xilf3 must be...
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