Article
[GST polymorphism and cytogenetic changes in lung tissues of lung cancer patients].
TSitologiia i genetika - 1 Jan 2000
Chakova N N, Mikhalenko E P, Polonetskaia S N, Chebotareva N V, Demidchik Iu E, Zhilko A A, Kvitko O V, Krupnova E V
Abstract excerpt
Carriers of GSTTI gene deletion were found to be more subjected to a risk of emerging non-small-cell lung cancer (NSLC) than those of normal GSTT1(+) genotype. Study on the relation between GST gene polymorphism and cytogenetic indices in lung cancer patients has shown a significant excess of the group average level in cells with micronuclei in NSLC patients with GSTTI(-). The frequency of cells with micronuclei...
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