Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene knockout of insulin-regulated aminopeptidase: loss of the specific binding site for angiotensin IV and age-related deficit in spatial memory.

Neurobiology of learning and memory - 1 Jan 2010

Albiston Anthony L, Fernando Ruani N, Yeatman Holly R, Burns Peta, Ng Leelee, Daswani Dina, Diwakarla Shanti, Pham Vi, Chai Siew Yeen

Abstract excerpt

The AT(4) ligands, angiotensin IV and LVV-hemorphin 7, elicit robust effects on facilitating memory by binding to a specific site in the brain historically termed the angiotensin AT(4) receptor. The identification of the AT(4) receptor as insulin-regulated aminopeptidase (IRAP) is controversial,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiotensin II
Share to Glucose Transporter Type 4

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Maze Learning

Share to Memory Disorders

Share to Neuropsychological Tests

Share to Receptors, Angiotensin

Share to Recognition, Psychology

Share to Space Perception

Source

Identifiers

PMID: 19660563
DOI: 10.1016/j.nlm.2009.07.011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19660563-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene knockout of insulin-regulated aminopeptidase: loss of the specific binding site for angiotensin IV and age-related deficit in spatial memory.PMID 19660563Read ↗

Cellular targets for angiotensin II fragments: pharmacological and molecular evidenceSemantic proximity Read ↗

Angiotensin mutant mice: a focus on the brain renin-angiotensin system.Semantic proximity Read ↗

Region- and age-specific deficits in gamma-aminobutyric acidergic neuron development in the telencephalon of the uPAR(-/-) mouse.Semantic proximity Read ↗

Behavioural phenotype of histamine H4 receptor knockout mice: Focus on central neuronal functions.Semantic proximity Read ↗

Neuronal cell adhesion molecule deletion induces a cognitive and behavioral phenotype reflective of impulsivity.Semantic proximity Read ↗

Central overexpression of angiotensin AT(1A) receptors prevents dopamine D(2) receptor regulation of alcohol consumption in mice.Semantic proximity Read ↗

Lack of angiotensin II conversion to angiotensin III increases water but not alcohol consumption in aminopeptidase A-deficient mice.Semantic proximity Read ↗

Varying intertrial interval reveals temporally defined memory deficits and enhancements in NTAN1-deficient mice.Semantic proximity Read ↗

Loss of EphA4 impairs short-term spatial recognition memory performance and locomotor habituation.Semantic proximity Read ↗

Deletion of insulin-regulated aminopeptidase in mice decreases susceptibility to pentylenetetrazol-induced generalized seizures.Semantic proximity Read ↗

Electrophysiological and behavioral phenotype of insulin receptor defective mice.Semantic proximity Read ↗

Deletion of the kinase domain from death-associated protein kinase enhances spatial memory in mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.