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Article

A novel endoplasmic reticulum export signal: proline at the +2-position from the signal peptide cleavage site.

The Journal of biological chemistry - 2 Oct 2009

Tsukumo Yoshinori, Tsukahara Satomi, Saito Sakae, Tsuruo Takashi, Tomida Akihiro

Abstract excerpt

NUCB1 (nucleobindin 1) is a Golgi-localized soluble protein with a signal peptide and multiple functional domains. We reported recently that NUCB1 is a negative regulator of the unfolded protein response that activates various endoplasmic reticulum (ER)-originating signaling pathways. In that report, we also showed that Golgi localization of NUCB1 was essential to regulate the unfolded protein response. However,...

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Identifiers

PMID: 19656946
DOI: 10.1074/jbc.M109.021592
PMCID: PMC2785679

Genes

NUCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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