Article
Activation of the Arabidopsis membrane-bound transcription factor bZIP28 is mediated by site-2 protease, but not site-1 protease.
The Plant journal : for cell and molecular biology - 1 Aug 2017
Iwata Yuji, Ashida Makoto, Hasegawa Chisa, Tabara Kazuki, Mishiba Kei-Ichiro, Koizumi Nozomu
Abstract excerpt
The unfolded protein response (UPR) is a homeostatic cellular response conserved in eukaryotic cells to alleviate the accumulation of unfolded proteins in the endoplasmic reticulum (ER). Arabidopsis bZIP28 is a membrane-bound transcription factor activated by proteolytic cleavage in response to ER stress, thereby releasing its cytosolic portion containing the bZIP domain from the membrane to translocate into the...
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