Article
Monoclonal antibody neutralization escape mutants of respiratory syncytial virus with unique alterations in the attachment (G) protein.
The Journal of general virology - 1 Mar 1998
Walsh E E, Falsey A R, Sullender W M
Abstract excerpt
Five monoclonal antibody (MAb) neutralization escape mutants of respiratory syncytial virus (RSV) were produced by growing the Long strain RSV (group A virus) in the presence of a neutralizing, group cross-reactive MAb specific for the attachment protein (G). Four viruses (RSV-2, -6, -14 and -15)...
Topics
- Amino Acid Sequence
- Antibodies, Monoclonal
- Attachment Sites, Microbiological
- Base Sequence
- Blotting, Western
- Fluorescent Antibody Technique, Indirect
- HN Protein
- Humans
- Molecular Sequence Data
- Mutation
- Respiratory Syncytial Viruses
- Tumor Cells, Cultured
- Viral Envelope Proteins
- Viral Proteins