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Article

The major histocompatibility complex conserved extended haplotype 8.1 in AIDS-related non-Hodgkin lymphoma.

Journal of acquired immune deficiency syndromes (1999) - 1 Oct 2009

Aissani Brahim, Ogwaro Kisani M, Shrestha Sadeep, Tang Jianming, Breen Elizabeth C, Wong Hui-Lee, Jacobson Lisa P, Rabkin Charles S, Ambinder Richard F, Martinez-Maza Otoniel, Kaslow Richard A

Abstract excerpt

BACKGROUND: Two single nucleotide polymorphisms (SNPs) in adjacent genes, lymphotoxin alpha (LTA +252G, rs909253 A>G) and tumor necrosis factor (TNF -308A, rs1800629 G>A), form the G-A haplotype repeatedly associated with increased risk of non-Hodgkin lymphoma (NHL) in individuals uninfected with HIV-1. This association has been observed alone or in combination with human leukocyte antigens HLA-B*08 or...

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Identifiers

PMID: 19654554
DOI: 10.1097/QAI.0b013e3181b017d5
PMCID: PMC3015185

Genes

LTA
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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