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Article

Variation in effects of non-Hodgkin lymphoma risk factors according to the human leukocyte antigen (HLA)-DRB1*01:01 allele and ancestral haplotype 8.1.

PloS one - 1 Jan 2011

Wang Sophia S, Lu Yani, Rothman Nathaniel, Abdou Amr M, Cerhan James R, De Roos Anneclaire, Davis Scott, Severson Richard K, Cozen Wendy, Chanock Stephen J, Bernstein Leslie, Morton Lindsay M, Hartge Patricia

Abstract excerpt

Genetic variations in human leukocyte antigens (HLA) are critical in host responses to infections, transplantation, and immunological diseases. We previously identified associations with non-Hodgkin lymphoma (NHL) and the HLA-DRB1*01:01 allele and extended ancestral haplotype (AH) 8.1 (HLA-A*01-B*08-DR*03-TNF-308A). To illuminate how HLA alleles and haplotypes may influence NHL etiology, we examined potential...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22096508
DOI: 10.1371/journal.pone.0026949
PMCID: PMC3212525

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TNF

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