Article
Dysfunction in ABCB1A has only a weak effect on susceptibility to dextran sulfate sodium-induced colitis in SAM strains.
Experimental animals - 1 Jul 2009
Zhang Guohong, Fu Xiaoying, Takeda Toshio, Higuchi Keiichi, Mori Masayuki
Abstract excerpt
Genetic alterations in the gene for ATP-binding cassette, sub-family B (MDR/TAP), member 1A (ABCB1A) determine susceptibility to colitis in mice and humans. We investigated the influence of ABCB1A dysfunction on susceptibility to dextran sulfate sodium (DSS)-induced colitis by using Senescence-Ac...
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