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Article

Age-related morphological and functional changes in the small intestine of senescence-accelerated mouse.

Experimental gerontology - 15 Jun 2022

Suzuki Takuji, Aoki Kai, Shimokobe Kotomi, Omiya Shoko, Funayama Chiharu, Takahashi Takumi, Kato Minori

Abstract excerpt

The ability of the small intestine to perform various functions, such as digestion/absorption of nutrients, gradually declines with age. However, the mechanism that causes intestinal senescence remains unclear. Therefore, age-related changes in the jejunum and ileum were evaluated using senescence-accelerated mouse (SAM) strains that possess characteristic phenotypes of aging. In particular, to understand how...

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PMID: 35378239
DOI: 10.1016/j.exger.2022.111795

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