Article
Genomic analysis reveals few genetic alterations in pediatric acute myeloid leukemia.
Proceedings of the National Academy of Sciences of the United States of America - 4 Aug 2009
Radtke Ina, Mullighan Charles G, Ishii Masami, Su Xiaoping, Cheng Jinjun, Ma Jing, Ganti Ramapriya, Cai Zhongling, Goorha Salil, Pounds Stanley B, Cao Xueyuan, Obert Caroline, Armstrong Jianling, Zhang Jinghui, Song Guangchun, Ribeiro Raul C, Rubnitz Jeffrey E, Raimondi Susana C, Shurtleff Sheila A, Downing James R
Abstract excerpt
Pediatric de novo acute myeloid leukemia (AML) is an aggressive malignancy with current therapy resulting in cure rates of only 60%. To better understand the cause of the marked heterogeneity in therapeutic response and to identify new prognostic markers and therapeutic targets a comprehensive li...
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