Asp327Asn polymorphism of sex hormone-binding globulin gene is associated with systemic lupus erythematosus incidence.

doi:10.1007/s11033-009-9639-7

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Article

Asp327Asn polymorphism of sex hormone-binding globulin gene is associated with systemic lupus erythematosus incidence.

Molecular biology reports - 1 Jan 2010

Piotrowski Piotr, Gasik Robert, Lianeri Margarita, Cieślak Dorota, Wudarski Mariusz, Hrycaj Paweł, Łacki Jan K, Jagodziński Paweł P

Abstract excerpt

Endogenous sex hormones have been observed to have a role in systemic lupus erythematosus (SLE) predisposition. Sex hormone-binding globulin (SHBG) regulates the bioavailability of sex hormones to target tissues. Therefore, we examined the distribution of the SHBG functional polymorphism Asp327Asn (rs6259) in SLE patients (n = 150) and controls (n = 150) in a Polish population. We found a contribution of the...

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PMID: 19649728
DOI: 10.1007/s11033-009-9639-7

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SHBG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Asp327Asn polymorphism of sex hormone-binding globulin gene is associated with systemic lupus erythematosus incidence.PMID 19649728Read ↗

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