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Article

Redox-sensitive cysteines bridge p300/CBP-mediated acetylation and FoxO4 activity.

Nature chemical biology - 1 Sept 2009

Dansen Tobias B, Smits Lydia M M, van Triest Miranda H, de Keizer Peter L J, van Leenen Dik, Koerkamp Marian Groot, Szypowska Anna, Meppelink Amanda, Brenkman Arjan B, Yodoi Junji, Holstege Frank C P, Burgering Boudewijn M T

Abstract excerpt

Cellular damage invoked by reactive oxygen species plays a key role in the pathobiology of cancer and aging. Forkhead box class O (FoxO) transcription factors are involved in various cellular processes including cell cycle regulation, apoptosis and resistance to reactive oxygen species, and studi...

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PMID: 19648934
DOI: 10.1038/nchembio.194

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19648934-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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