Article
Relationship between TP53 tumour suppressor gene mutations and smoking-related bulky DNA adducts in a lung cancer study population from Hungary.
Mutagenesis - 1 Nov 2009
Anna Lívia, Holmila Reetta, Kovács Katalin, Gyorffy Erika, Gyori Zoltán, Segesdi Judit, Minárovits János, Soltész Ibolya, Kostic Szilárd, Csekeo Attila, Husgafvel-Pursiainen Kirsti, Schoket Bernadette
Abstract excerpt
Lung cancer rate in Hungary is one of the highest in the world among men and also very high among women, for reasons not clearly understood yet. The aim of the study was to explore characteristics of DNA damage and TP53 gene mutations in lung cancer from Hungary. Tissue samples from 104 lung resections for lung cancer patients, both men and women, operated on for non-small cell lung cancer, specifically, primary...
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