Article
CD1d gene is a target for a novel amplicon at 1q22-23.1 in human hepatocellular carcinoma.
Molecular biology reports - 1 Jan 2010
Zhang Shi-Guang, Song Wen-Qin, Gao Ying-Tang, Yang Bin, Du Zhi
Abstract excerpt
Genome copy number variation (CNV) is one of the mechanisms to regulate the expression level of genes which contributes to the development and progression of cancer. In order to investigate the regions of high-level amplification and potential target genes within these amplicons in hepatocellular carcinoma (HCC), we analyzed HCC cell line (TJ3ZX-01) for CNV regions at the whole genome level using GeneChip Human...
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