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Metallothionein MT1M is a tumor suppressor of human hepatocellular carcinomas

12 Sept 2012

Abstract excerpt

Members of the metallothionein (MT) family are short, cysteine-rich proteins involved in metal metabolism and detoxification, suggesting that MT proteins protect cells from damage caused by electrophilic carcinogens and thereby constitute a critical surveillance system against carcinogenesis. However, the roles of MT proteins in human hepatocellular carcinoma (HCC) are not fully understood. We identified a member...

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PMID: 22971577
DOI: 10.1093/carcin/bgs287

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