Individualization of lymph node dissection in RET (rearranged during transfection) carriers at risk for medullary thyroid cancer: value of pretherapeutic calcitonin levels.

Abstract excerpt

OBJECTIVE: This study sought to define the need for lymph node dissection in Rearranged during Transfection (RET) carriers at risk for hereditary medullary thyroid cancer. SUMMARY BACKGROUND DATA: Controversy surrounds the need for lymph node dissection to complement thyroidectomy in RET carriers. METHODS: Integration of molecular, biochemical, histopathologic, and clinical information from 308 RET carriers...

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