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Article

Characterization of the RET protooncogene transmembrane domain mutation S649L associated with nonaggressive medullary thyroid carcinoma.

European journal of endocrinology - 1 Jun 2008

Colombo-Benkmann Mario, Li Zhenpeng, Riemann Burkhard, Hengst Karin, Herbst Hermann, Keuser Roger, Gross Ute, Rondot Susanne, Raue Friedhelm, Senninger Norbert, Pützer Brigitte M, Frank-Raue Karin

Abstract excerpt

CONTEXT: For rare and novel RET mutations associated with hereditary medullary thyroid carcinoma (MTC), clinical and functional studies are needed to classify the RET mutation into one of the three clinical risk groups. OBJECTIVE: We analyzed proliferative properties and clinical implications ass...

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Source

Identifiers

PMID: 18322301
DOI: 10.1530/EJE-07-0817

Genes

RET

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18322301-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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