Article
Prophylactic thyroidectomy in ethnic Chinese patients with multiple endocrine neoplasia type 2A syndrome after the introduction of genetic testing.
Hong Kong medical journal = Xianggang yi xue za zhi - 1 Oct 2009
Lau Gregory S K, Lang Brian H H, Lo C Y, Tso Annette, Garcia-Barcelo Merce M, Tam Paul K, Lam Karen S L
Abstract excerpt
OBJECTIVE: To evaluate the impact of genetic testing in the management of familial multiple endocrine neoplasia 2A patients. DESIGN: Retrospective study. SETTING: University teaching hospital, Hong Kong. PATIENTS: Twenty-two patients from eight multiple endocrine neoplasia 2A families underwent prophylactic total thyroidectomy based on a positive RET mutation genetic testing. All mutations were located at codon...
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